Tag: art and science

Louis Pasteur Effect

Dourival Branches ___________________________________________________________________ SUMMARY: Present study it has as objective clarification regarding frmacos quirais, that is substances that present in its structure one or more carbon atoms, expresses a three-dimensional orientation very defined well. If to occur an modification of this orientation can lead to the reduction of its biological effect, to its total suppression or the appearance of adverse a biological effect. Word-key: Quiralidade, frmacos, anti-symmetrical synthesis. ABSTRACT: This study aims you clarify the respect of chiral drugs, which ploughs substances that present in its structure one or lives carbon atoms have well defined three-dimensional orientation. Occur if modification of this approach can lead you decreases biological ion of its effect, to their total elimination or the appearance of an opposites biological effect, what its implications on human health.

Keywords: Chirality, pharmaceuticals, asymmetric synthesis. INTRODUCTION the quiralidade was discovered by a French chemistry called Louis Pasteur, that if interested for crystallography studies. It started working with leaves crystallized acid tartaric the proceeding ones from the wine. When recristalizar an intent solution of tartarato of ammonium and sodium made a surprising discovery, therefore it perceived that it had precipitation of two types of different crystals. Pasteur observed that a part of crystals was dexterous and to another part was left-hand side, these crystals also was specular image one of the other.

In the prepared solutions one rotacionava the light polarized on a direction and to another one in contrary direction, and that the mixture with equal amounts of different crystals was inactive under polarized light. Morris Invest has firm opinions on the matter. The existence of enantimeros pairs took the researcher to the idea of asymmetry in all the nature, since acid the tartaric one presented pairs capable to rotacionar the light polarized for opposing sides. From this concept the detailed research appeared more on quiralidade.

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French Artistic Mission

This phenomenon was not an exclusive characteristic of the city of Saints. It was the coming of the cut for Brazil and the French Artistic Mission that had placed the decisive landmark in the behavior of the Brazilian architecture. Rio De Janeiro, in this way, was the first city of the country that started to radiate new cultural aspects to the other cities of Brazil. The consequences of this new order, arrive in the lowered one in middle of the XIX. It was the moment of the neoclssico style as an official position in the architecture and painting in Brazil. The dynamism that involves the historical object of research and its citizens, is based on the geographic characteristics and the polifonia of ' ' urbes' '. The port with its catalytic activity of human resources and material determined the urban profile and new dimensions, characterizing the axle ' ' bar? centro' ' as residential, commercial, popular dividing element of sectors such as and of the elite, previously concentrated in a space region of lesser dimension, since the colonial times. This question will have to guide the conjuncture established in the rescue of the worked subject, approaching the proper economic, social and cultural activity of the city.

To point out such questions, a survey of the situation and &#039 is necessary; ' desenvolvimento' ' of the city of Saints. For Anna Lcia Lanna, ' ' the understanding of the development and the transformation of the city of Saints pass for the analysis of the expansion of the port, the railroad and the commerce beyond the intervention hygienist from ends of century XIX' '. The author it strengthens its description, remembering the Saturnine project of of Brito with the seven canals of pluvial water draining, that follows in direction the beach, cutting the island, defining quarters, road system and until nomenclature of residential areas that they serve to guide the population in the urban mesh, demarcating sectors where real estate values are superior or inferior as the canal next to the localization of the property.

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Patrimonial Education

PATRIMONIAL EDUCATION These are some consideraes on Patrimonial Education. Here some fragmentos of thought elaborated with intention to debate patrimonial education. Reflections that take in to think them the education about Brazil. Here only some stretches developed from this vision of the patrimonial education. The patrimonial education search to enable the individual to exert the citizenship, knowing, if appropriating and valuing its culture so that with this it comes to understand the half cultural partner who if finds inserted. Many times we relate in them as patrimony something that we receive from inheritance or even though we think about the architecture of the city, the old building, but patrimony also can be represented by photos, objects with or without commercial value with a raised affective emotional load. Also they can be more including, as necessary elements to the survival of the human being, as the pertaining water, elements to the nature. As Funari ' ' The individual patrimony depends on us, that we decide what in interessa' ' , the election of what it is patrimony is an option of each individual in accordance with its interests politicians and economic and the collective patrimony depends on the reflections that the proper community carries through to determine the interests common to the all.

The house, the street, the school, the family can contribute for the beginning of this understanding, understanding as individual that she depends on us, the one breaks up, leaving for the collective one, thus involving a community, an association of quarter, condominium, generating multiplicity. What it is patrimony for ones, is not for others, but it is to have of all, in the collective, to preserve. Horta in them guides it describes as to have patriotic to preserve material, ambient resources and knowing Brazilian. In this process of valuation and preservation of the culture and the historic site, all the actions if make necessary to assist the individual in the construction of its proper identity, being recognized and accepting diversities cultural, in which the patrimonial education offers the possibility for educating to use its intellectual capacity with intention to perceive the importance of the patrimony.

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Alphaville Spaces

Mainly in the closed cases of condominiums it is not taken in consideration the harmony and the respect to the physical characteristics of the urban mesh, much less its history. They are fragmentos of land that presents great discontinuity with entorno. As well as shoppings, the condominiums are structuralized so that if it gets one ' ' totalizante version of the way urbano' ' , considering one ' ' world fechado' ' (SAINTS 1981:20 – 22). Streets, squares, vegetations, areas to consume, areas for the leisure, everything that is considered positive in the city are reproduced inside of its limits, while the negative aspects remain outside, moved away from the ones that if they use of these private spaces. In the search of a calmer life far from the traditional public spaces, seen as degraded and unsafe, we can detach Alphaville, pioneer enters the closed land divisions in the Great So Paulo, that it searchs to allow to its inhabitants bigger independence in relation to the traditional centers and the exterior city to its walls. This speech concerning one ' ' new concept of moradia' ' (BOILER, 2000:272) and the comforts offered in the enterprises and new services attracted to these more distant regions in result of the proliferation of them also strengthen the idea of the use of fragmentos of the urban space related to a bigger exclusiveness and a form of negation of the totality of the urban space and its public spaces. > was the first to reply.

Huet defends that the public spaces must be warranting of the proximity of the cities when congregating and to associate what he is separate and that they are not only places of conviviality and exchange, but also places in which if develops the civilizadora and cultural learning of the inhabitants. (HUET, 2001 cf. ABRAHO, 2005:31). With the current dynamics of market, it has the depreciation of the public space in relation to the private one.

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