So although what happens in one can apparently caused by what happens in the other, the truth is that they are two entities that only obey their own laws, even when their behavior appears related to an outside observer. Professor Rita McGrath may also support this cause. The radical interactionist dualism: The thesis of Popper and Eccles in "The Self and its Brain", Popper and Eccles made a modern version of the dualism which is known as "radical interactionist dualism." There are still some difficulties to clearly frame the radical interactionist dualism or property dualism substantial dualism, though its plot seems oriented more to the last alternative. The general hypothesis is that the mind is self-conscious other than the brain, but capable of exerting a higher role of interpretation and control of neuronal processes. Indeed, the mind, on the one hand, is responsible for making a final synthesis product of brain activity, an operation that the brain is unable to perform and also is able to direct certain flows of brain activities. The mind: It is different to the brain (basic ontological budget) may be partly influenced by the brain (bottom-up causality restricted) Select the products and makes the synthesis cerebral end of the activity (top-down causation) can influence the brain ( top-down causation) According to Eccles, the brain is a structure complex enough to account for the phenomena associated with consciousness, so it is necessary to postulate the existence of an autonomous self-conscious mind than the brain. This would be an immaterial reality but able to exercise a higher role of interpretation and control of neuronal processes.